Promis Centre
publications and reports








publications and reports

Peters BH, Molnár F, Ketolainen J. Structural attributes of model protein formulations prepared by rapid freeze-drying cycles in a microscale heating stage. Eur. J. Pharm. Biopharm. 2014, DOI: 10.1016/j.ejpb.2014.02.016.

Turunen E, Korhonen O, Lehto VP, Kauppinen A, Ahtiainen H, Järvinen K, Jarho P. Effect of storage on the dissolution rate of a fast-dissolving perphenazine/β-cyclodextrin complex. J. Pharm. Pharmacol. 2014, 66, 367-77.

Kauppinen A, Toiviainen M, Aaltonen J, Korhonen O, Järvinen K, Juuti M, Pellinen R and Ketolainen J. Microscale Freeze-Drying with Raman Spectroscopy as a Tool for Process Development. Anal. Chem. 2013, 85, 2109-2116.

Kauppinen A, Toiviainen M, Korhonen O, Aaltonen J, Järvinen K, Paaso J, Juuti M and Ketolainen J. In-Line Multipoint Near-Infrared Spectroscopy for Moisture Content Quantification during Freeze-Drying. Anal. Chem. 2013, 85, 2377-2384.

Leskinen JT, Simo-Pekka Simonaho SP, Hakulinen M, Ketolainen J. Real-time tablet formation monitoring with ultrasound measurements in eccentric single station tablet press. Int. J. Pharm. 2013, 442, 27-34.

Laitinen R: Feasibility of the PROMIS continuous pharmaceutical production line in emergency conditions and its commercialisation potential in developing countries. Human Security Finland report. 3.10.2013 version 1.0.

Ervasti T, Silfsten P, Ketolainen J, Peiponen KE. A study on the resolution of a terahertz spectrometer for the assessment of the porosity of pharmaceutical tablets. Appl. Spectrosc. 2012, 66, 319-23.

Pajula K, Lehto VP, Ketolainen J, Korhonen O. Computational approach for fast screening of small molecular candidates to inhibit crystallization in amorphous drugs. Mol. Pharm. 2012, 9, 2844-55.

Simonaho SP, Takala TA, Kuosmanen M, Ketolainen J. Ultrasound transmission measurements for tensile strength evaluation of tablets. Int. J. Pharm. 2011, 409, 104-110.

Pajula K, Taskinen M, Lehto VP, Ketolainen J, Korhonen O. Predicting the formation and stability of amorphous small molecule binary mixtures from computationally determined Flory-Huggins interaction parameter and phase diagram. Mol. Pharm. 2010, 7, 795-804.

Leskinen JT, Simonaho SP, Hakulinen M, Ketolainen J. In-line ultrasound measurement system for detecting tablet integrity. Int. J. Pharm. 2010, 400, 104-113.

19.09.2014 Mobile Course on QbD and PAT

Mobile Course on QbD and PAT

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27.05.2014 PROMIS Centre operations were presented for Ambassador of Ireland to Finland, HE Dónal Denham

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Promis centre University of Eastern Finland VTT Savonia University of applied sciences