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publications and reports

Peters BH, Molnár F, Ketolainen J. Structural attributes of model protein formulations prepared by rapid freeze-drying cycles in a microscale heating stage. Eur. J. Pharm. Biopharm. 2014, DOI: 10.1016/j.ejpb.2014.02.016.

Turunen E, Korhonen O, Lehto VP, Kauppinen A, Ahtiainen H, Järvinen K, Jarho P. Effect of storage on the dissolution rate of a fast-dissolving perphenazine/β-cyclodextrin complex. J. Pharm. Pharmacol. 2014, 66, 367-77.

Kauppinen A, Toiviainen M, Aaltonen J, Korhonen O, Järvinen K, Juuti M, Pellinen R and Ketolainen J. Microscale Freeze-Drying with Raman Spectroscopy as a Tool for Process Development. Anal. Chem. 2013, 85, 2109-2116.

Kauppinen A, Toiviainen M, Korhonen O, Aaltonen J, Järvinen K, Paaso J, Juuti M and Ketolainen J. In-Line Multipoint Near-Infrared Spectroscopy for Moisture Content Quantification during Freeze-Drying. Anal. Chem. 2013, 85, 2377-2384.

Leskinen JT, Simo-Pekka Simonaho SP, Hakulinen M, Ketolainen J. Real-time tablet formation monitoring with ultrasound measurements in eccentric single station tablet press. Int. J. Pharm. 2013, 442, 27-34.

Laitinen R: Feasibility of the PROMIS continuous pharmaceutical production line in emergency conditions and its commercialisation potential in developing countries. Human Security Finland report. 3.10.2013 version 1.0. http://www.humansecurityfinland.com/documents/14286/33375/PromisReport_2013.pdf/adde9c64-4893-492f-b277-a78d4952a6c2

Ervasti T, Silfsten P, Ketolainen J, Peiponen KE. A study on the resolution of a terahertz spectrometer for the assessment of the porosity of pharmaceutical tablets. Appl. Spectrosc. 2012, 66, 319-23.

Pajula K, Lehto VP, Ketolainen J, Korhonen O. Computational approach for fast screening of small molecular candidates to inhibit crystallization in amorphous drugs. Mol. Pharm. 2012, 9, 2844-55.

Simonaho SP, Takala TA, Kuosmanen M, Ketolainen J. Ultrasound transmission measurements for tensile strength evaluation of tablets. Int. J. Pharm. 2011, 409, 104-110.

Pajula K, Taskinen M, Lehto VP, Ketolainen J, Korhonen O. Predicting the formation and stability of amorphous small molecule binary mixtures from computationally determined Flory-Huggins interaction parameter and phase diagram. Mol. Pharm. 2010, 7, 795-804.

Leskinen JT, Simonaho SP, Hakulinen M, Ketolainen J. In-line ultrasound measurement system for detecting tablet integrity. Int. J. Pharm. 2010, 400, 104-113.

 
19.09.2014 Mobile Course on QbD and PAT

Mobile Course on QbD and PAT

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27.05.2014 PROMIS Centre operations were presented for Ambassador of Ireland to Finland, HE Dónal Denham

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Promis centre University of Eastern Finland VTT Savonia University of applied sciences